Effects of water to binder ratio (m_W/m_B), types and content of mineral admixtures on autogenous relative humidity (ARH) change of concrete resulting from self-desiccation were studied. The parameters of coefficient of mineral self-desiccation-effect k and effective water to binder ratio r_e were proposed, and experimental results were fitted non-linearly and analyzed using these proposed parameters. It is indicated from the results that ARH reduction of concrete with ages inereases with decrease of water to binder ratio. The ARH change laws of concrete with water to binder ratio lower than 0.4 can be expressed with a non-linear equation. The extent to the effect of types and content of mineral admixtures on ARH reduction of concrete resulting from self-desiccation can be reflected by the parameter of the effective water to binder ratio r_e effectively.